1360095-78-8

Basic information

• Product Name: (R)-N-methyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
• Synonyms: (R)-N-methyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide
• CAS NO: 1360095-78-8
• Molecular Weight: 272.27
• Mol File: 1360095-78-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-N-methyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-methyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide(1360095-78-8)
• EPA Substance Registry System: (R)-N-methyl-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide(1360095-78-8)

Safety Data

• Hazardous Substances Data: 1360095-78-8(Hazardous Substances Data)

Upstream product

• 1360095-75-5 (R)-tert-butyl 3-((6-(trifluoromethyl)-pyridazin-3-yl)(methyl)amino)pyrrolidine-1-carboxylate 
• 1360095-59-5 (R)-tert-butyl 3-(N-methyl-2-(trifluoromethyl)benzamido)pyrrolidine-1-carboxylate 
• 199336-83-9 (R)-3-(methylamino)pyrrolidine-1-carboxylic acid tert-butyl ester 
• 433-97-6 2-trifluoromethylbenzoic acid 

Downstream Products

• 1360091-94-6 (R)-N-(1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)-N-methyl-2-(trifluoromethyl)benzamide 

Relevant articles and documents

PYRROLOPYRIMIDINE COMPOUNDS AND USES THEREOF

The present disclosure provides pyrrolopyrimidine compounds and methods of use therefor. For example, the disclosure provides certain pyrrolopyrimidine compounds capable of inhibiting JAK kinases. The disclosure further provides the pharmaceutical compositions containing these pyrrolopyrimidine compounds, and use of these pyrrolopyrimidine compounds in the treatment of disorders or diseases, such as inflammatory diseases and cancer.

PYRROLOPYRIMIDINE COMPOUNDS AND USES THEREOF

Disclosed are pyrrolopyrimidine compounds of formula (I) capable of inhibiting JAK kinase, wherein R1, R2 and m are defined as in the description. The pharmaceutical compositions containing said pyrrolopyrimidine compounds and uses of said pyrrolopyrimidine compounds in the treatment of disorders or diseases such as inflammatory diseases and cancers are also disclosed.