136032-07-0

Basic information

• Product Name: (-)-<(1R,2S)-2-phenylcyclohex-1-yl>phenylglyoxalate
• Synonyms: (-)-<(1R,2S)-2-phenylcyclohex-1-yl>phenylglyoxalate
• CAS NO: 136032-07-0
• Molecular Weight: 308.377
• Mol File: 136032-07-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (-)-<(1R,2S)-2-phenylcyclohex-1-yl>phenylglyoxalate(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-<(1R,2S)-2-phenylcyclohex-1-yl>phenylglyoxalate(136032-07-0)
• EPA Substance Registry System: (-)-<(1R,2S)-2-phenylcyclohex-1-yl>phenylglyoxalate(136032-07-0)

Safety Data

• Hazardous Substances Data: 136032-07-0(Hazardous Substances Data)

Upstream product

• 98919-68-7 (1R,2S)-trans-2-phenylcyclohexanol 
• 611-73-4 Benzoylformic acid 
• 1074-12-0 phenylglyoxal hydrate 

Downstream Products

• 142798-11-6 2-Hydroxy-2-phenyl-propionic acid (1R,2S)-2-phenyl-cyclohexyl ester 
• 142798-12-7 (R)-2-Hydroxy-2-phenyl-butyric acid (1R,2S)-2-phenyl-cyclohexyl ester 
• 142798-12-7 (S)-2-Hydroxy-2-phenyl-butyric acid (1R,2S)-2-phenyl-cyclohexyl ester 
• 109462-07-9 Hydroxy-phenyl-acetic acid (1R,2S)-2-phenyl-cyclohexyl ester 
• 161634-47-5 (1R,2S)-trans-2-Phenylcyclohexyl 2-oxophenylacetate tosylhydrazone 
• 109462-07-9 (1R,2S)-trans-2-Phenylcyclohexyl (R)-mandelate 
• 161634-50-0 (1R,2S)-trans-2-Phenylcyclohexyl 2-diazophenylacetate 
• 3966-31-2 (R)-2-hydroxy-2-phenylbutyric acid 
• 51559-16-1 α-hydroxy-α-phenyl-β-methylbutanoic acid 
• 117195-36-5 (R)-2-Phenyl-2-hydroxyhexanoic acid 
• 97690-17-0 acide phenyl-2 hydroxy-2 methyl-4 pentanoique 

Relevant articles and documents

Selective Formation of Functionalized α-Quaternary Malononitriles toward 5,5-Disubstituted Pyrrolopyrimidinones

A modular, selective approach to complex α-tertiary substituted malononitriles is reported. The method takes advantage of β-ester-substituted α,α-dinitrile alkenes as highly reactive, chemoselective electrophiles for 1,4-additions with organometallic nucleophiles to produce functionally and sterically dense all-carbon quaternary centers. In the presence of a chiral ester auxiliary bearing an aromatic ring, the 1,4-addition occurs with good to excellent selectivity due to favorable cation-π interactions. The highly functionalized malononitriles represent versatile building blocks and can be applied toward efficient, highly selective syntheses of 5,5-disubstituted pyrrolopyrimidinones.

ENANTIOSELECTIVE SYNTHESIS OF α- AND β-HYDROXY ACIDS USING trans-2-PHENYLCYLOHEXAN-1-OL AS CHIRAL AUXILIARY

trans-2-Phenylcyclohexanol has been used as a chiral auxiliary for the preparation of α- and β-hydroxy acids in 85 - 100 percent and 11 - 89 percent enantiomeric purities respectively.