136058-30-5Relevant articles and documents
Compounds
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, (2008/06/13)
Polymers of structure: in which,R1 and R2 are each C1 4alkyl, or one is C1 4alkyl and the other is -(CH2)nR3;, n is 2 to 12; R4 and R5 are the same or different and are each hydrogen, C1 4alkyl, C(=NH)NH2, or together with the nitrogen atom to which they are attached form a saturated or unsaturated ring optionally containing one or more further heteroatoms., R6, R7 and R8 are the same or different and are each hydrogen, C1 4alkyl or one of R6, R7 and R8 is C1 4alkyl and the other two together with the nitrogen atom to which they are attached form a saturated or unsaturated ring optionally containing one or more further heteroatoms;, a, b and c are numbers which indicate the relative molar percentages of the units present in said polymer, (b) being from 1 to 10 molar percent, and (c) being from 30 to 98 molar percent; and, X? is a counter ion,processes for their preparation, pharmaceutical compositions containing them and their use in therapy as cholesterol lowering agents.