1360804-49-4

Basic information

• Product Name: C₂₄H₂₄ClN₅O₉
• Synonyms: C₂₄H₂₄ClN₅O₉
• CAS NO: 1360804-49-4
• Molecular Weight: 561.936
• Mol File: 1360804-49-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₄ClN₅O₉(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₄ClN₅O₉(1360804-49-4)
• EPA Substance Registry System: C₂₄H₂₄ClN₅O₉(1360804-49-4)

Safety Data

• Hazardous Substances Data: 1360804-49-4(Hazardous Substances Data)

Upstream product

• 3056-18-6 (2R,3R,4R,5R)-4-(acetyloxy)-2-[(acetyloxy)methyl]-5-(2,6-dichloro-9H-purin-9-yl)tetrahydro-3-furanyl acetate 
• 621-84-1 O-benzyl carbamate 
• 16321-99-6 2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine 

Relevant articles and documents

Pd-catalysed amidation of 2,6-dihalopurine nucleosides. Replacement of iodine at 0 °c

Pd-catalysed reactions of 2-Cl, 2-Br and 2-I derivatives of a 6-chloropurine nucleoside with benzamide have been compared, using Pd 2dba3, Xantphos and Cs2CO3 in toluene, between 20 and 80 °C. The reactivity order was 2-I > 2-Br > 6-Cl ? 2-Cl. The 2-I substituent could be replaced even at 0 °C, under conditions disclosed here for the first time. On the other hand, the replacement of the chlorine atom at position 2 (2-Cl) required 110 °C.