1360923-54-1 Usage
Description
(R)-methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate is a complex chiral chemical compound with the molecular formula C18H16ClNO3S. It is characterized by its unique structure, which includes a methyl group, a 2-chlorophenyl group, and a 2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl group. (R)-methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate is of interest in pharmaceutical research and development due to its potential medicinal properties and biological activity.
Uses
Used in Pharmaceutical Research and Development:
(R)-methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate is used as a compound of interest in pharmaceutical research and development for its potential medicinal properties. Its unique chemical structure and biological activity make it a promising candidate for the treatment of various diseases and disorders.
Used in the Treatment of Various Diseases and Disorders:
(R)-methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate is used as a potential therapeutic agent for the treatment of various diseases and disorders. Its specific application type and reason for use will depend on the disease or disorder being targeted, as well as the results of further research and development.
Used in the Study of Chiral Molecules:
(R)-methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate is used as a subject of interest in the study of chiral molecules. Its non-superimposable mirror image and unique properties make it a valuable compound for understanding the behavior and applications of chiral molecules in various fields, including pharmaceuticals, materials science, and chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1360923-54-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,0,9,2 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1360923-54:
(9*1)+(8*3)+(7*6)+(6*0)+(5*9)+(4*2)+(3*3)+(2*5)+(1*4)=151
151 % 10 = 1
So 1360923-54-1 is a valid CAS Registry Number.
1360923-54-1Relevant articles and documents
Overcoming clopidogrel resistance: Discovery of vicagrel as a highly potent and orally bioavailable antiplatelet agent
Shan, Jiaqi,Zhang, Boyu,Zhu, Yaoqiu,Jiao, Bo,Zheng, Weiyi,Qi, Xiaowei,Gong, Yanchun,Yuan, Fang,Lv, Fusheng,Sun, Hongbin
experimental part, p. 3342 - 3352 (2012/06/04)
A series of optically active 2-hydroxytetrahydrothienopyridine derivatives were designed and synthesized as prodrugs of clopidogrel thiolactone in order to overcome clopidogrel resistance. The final compounds were evaluated for their inhibitory effect on ADP-induced platelet aggregation in rats. Compound 9a was selected for further in vitro and in vivo metabolism studies, since its potency was comparable to that of prasugrel and was much higher than that of clopidogrel. Preliminary pharmacokinetic study results showed that the bioavailability of clopidogrel thiolactone generated from 9a was 6-fold higher than that generated from clopidogrel, implying a much lower clinically effective dose for 9a in comparison with clopidogrel. In summary, 9a (vicagrel) holds great promise as a more potent and a safer antiplatelet agent that might have the following advantages over clopidogrel: (1) no drug resistance for CYP2C19 poor metabolizers; (2) lower dose-related toxicity due to a much lower effective dose; (3) faster onset of action.
