1363440-02-1Relevant articles and documents
A unified photoredox-catalysis strategy for C(sp3)-H hydroxylation and amidation using hypervalent iodine
Li, Guo-Xing,Morales-Rivera, Cristian A.,Gao, Fang,Wang, Yaxin,He, Gang,Liu, Peng,Chen, Gong
, p. 7180 - 7185 (2017)
We report a unified photoredox-catalysis strategy for both hydroxylation and amidation of tertiary and benzylic C-H bonds. Use of hydroxyl perfluorobenziodoxole (PFBl-OH) oxidant is critical for efficient tertiary C-H functionalization, likely due to the enhanced electrophilicity of the benziodoxole radical. Benzylic methylene C-H bonds can be hydroxylated or amidated using unmodified hydroxyl benziodoxole oxidant Bl-OH under similar conditions. An ionic mechanism involving nucleophilic trapping of a carbocation intermediate by H2O or CH3CN cosolvent is presented.
AZETIDINE DERIVATIVES
-
Paragraph 0424; 0425; 0426; 0427; 0428, (2013/06/28)
Azetidine derivatives of which the following is exemplary and their use in the treatment of obesity, diabetes or dyslipidemia.