1364398-15-1

Basic information

• Product Name: ethyl 4-methyl-2-(4-(2-methylpropyloxy)-3-cyanophenyl)-5-thiazolecarboxylate hydrochloride
• Synonyms: ethyl 4-methyl-2-(4-(2-methylpropyloxy)-3-cyanophenyl)-5-thiazolecarboxylate hydrochloride
• CAS NO: 1364398-15-1
• Molecular Weight: 380.895
• Mol File: 1364398-15-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-methyl-2-(4-(2-methylpropyloxy)-3-cyanophenyl)-5-thiazolecarboxylate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-methyl-2-(4-(2-methylpropyloxy)-3-cyanophenyl)-5-thiazolecarboxylate hydrochloride(1364398-15-1)
• EPA Substance Registry System: ethyl 4-methyl-2-(4-(2-methylpropyloxy)-3-cyanophenyl)-5-thiazolecarboxylate hydrochloride(1364398-15-1)

Safety Data

• Hazardous Substances Data: 1364398-15-1(Hazardous Substances Data)

Upstream product

• 25984-64-9 3-bromo-4-hydroxy-thiobenzamide 
• 2973-78-6 3-bromo-4-hydroxybenzylaldehyde 
• 2315-86-8 3-bromo-4-hydroxybenzonitrile 
• 144060-96-8 2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

IMPROVED PROCESS TO PREPARE ETHYL 4-METHYL-2-(4-(2-METHYLPROPYLOXY)-3-CYANOPHENYL)-5-THIAZOLECARBOXYLATE

Disclosed is a process for the preparation of Ethyl 4-methyl-2-(4-(2-methylpropyloxy)-3-cyanophenyl)-5-thiazolecarboxylate (I) the key intermediate for the preparation of [2-[3-cyano-4-(2-Methyl-propoxy)phenyl]-4-methyl-5-thiazole carboxylic acid (Febuxostat, I(A)) is approved under the trademark Uloric ? by the US Food and Drug Administration for the treatment of hyperuricemia and gouty arthritis.