1364511-68-1Relevant articles and documents
Palladium-Nanoparticles-Catalyzed Oxidative Annulation of Benzamides with Alkynes for the Synthesis of Isoquinolones
Sharma, Nidhi,Saha, Rajib,Parveen, Naziya,Sekar, Govindasamy
, p. 1947 - 1958 (2017)
A novel method to synthesize isoquinolones via oxidative annulation of N-alkoxy benzamides and alkynes using binaphthyl-stabilized palladium nanoparticles (Pd-BNP) as catalyst has been developed. This methodology affords various isoquinolone derivatives in good to excellent yields with high regioselectivities in the presence of air as oxidant. N-Methoxybenzothioamide was also found to undergo oxidative annulation with alkyne successfully and provided a sulfur analogue of isoquinolones in moderate yields. The Pd-BNP catalyst was easily recovered and reused up to four times without any apparent agglomeration. (Figure presented.).
A practical one-pot procedure for the synthesis of N-H isoquinolones
Lu, Shaonan,Lin, Yingfu,Zhong, Hongban,Zhao, Kang,Huang, Jianhui
supporting information, p. 2001 - 2005 (2013/04/23)
A practical one-pot procedure for the preparation of N-H isoquinolones has been developed. This 2-step process via C-H activation of N-alkoxyl benzamides and NaH-mediated dealkoxylation reaction has been demonstrated to be a high yielding alternative meth
