13649-16-6Relevant articles and documents
Hydroxamate inhibitor profiling of both zn2+- and ni2+-activated glyoxalase i metalloenzymes having diverse quaternary structures
Suttisansanee, Uthaiwan,Honek, John F.
, p. 843 - 852 (2017/08/07)
Background: The glyoxalase enzyme system is a critical component in the detoxification of cellular metabolically generated alpha-ketoaldehydes, such as methylglyoxal. Inhibitors of these enzymes have been shown to have potential in the development of anti
Glutathione N-hydroxycarbamoyl thioesters and method of inhibiting neoplastic growth
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, (2008/06/13)
A compound of the formula STR1 with R being hydrogen, alkyl, cycloalkyl or aryl, which may be substituted with halogen or alkyl, and R' and Ra being hydroxyl, or --O-alkyl, pharmaceutically acceptable salts thereof; or mixtures thereof. An anti
