1365221-52-8

Basic information

• Product Name: N-(4-fluorobenzyl)-6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine-3-carboxamide
• Synonyms: N-(4-fluorobenzyl)-6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine-3-carboxamide
• CAS NO: 1365221-52-8
• Molecular Weight: 433.46
• Mol File: 1365221-52-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(4-fluorobenzyl)-6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-fluorobenzyl)-6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine-3-carboxamide(1365221-52-8)
• EPA Substance Registry System: N-(4-fluorobenzyl)-6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine-3-carboxamide(1365221-52-8)

Safety Data

• Hazardous Substances Data: 1365221-52-8(Hazardous Substances Data)

Upstream product

• 298690-72-9 (rac)-2-(3-fluorophenyl)pyrrolidine 
• 1150566-27-0 6-chloroimidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester 
• 1365214-89-6 6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine-3-carboxylic acid 
• 140-75-0 para-fluorobenzylamine 

Relevant articles and documents

Development of subnanomolar radiofluorinated (2-pyrrolidin-1-yl)imidazo[1,2-b]pyridazine pan-Trk inhibitors as candidate PET imaging probes

Dysregulation of tropomyosin receptor kinases (TrkA/B/C) expression and signalling is recognized as a hallmark of numerous neurodegenerative diseases including Parkinson's, Huntington's and Alzheimer's disease. TrkA/B/C is known to drive tumorogensis and