1365759-94-9

Basic information

• Product Name: C₂₄H₂₅N₇O₄
• Synonyms: C₂₄H₂₅N₇O₄
• CAS NO: 1365759-94-9
• Molecular Weight: 475.507
• Mol File: 1365759-94-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₅N₇O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₅N₇O₄(1365759-94-9)
• EPA Substance Registry System: C₂₄H₂₅N₇O₄(1365759-94-9)

Safety Data

• Hazardous Substances Data: 1365759-94-9(Hazardous Substances Data)

Upstream product

• 14918-21-9 5-hexynonitrile 
• 1365759-81-4 C₁₈H₁₈N₆O₄ 
• 1365759-75-6 C₁₂H₉N₅O₂ 
• 1365759-70-1 C₁₇H₁₇N₅O₄ 
• 1246303-86-5 t-butyl 3-(4-aminophenyl)-4-oxo-6,7-dihydroisoxazolo[4,5-c]pyridine-5(4H)-carboxylate 
• 1246303-72-9 t-butyl 3-(4-nitrophenyl)-4-oxo-6,7-dihydroisoxazolo[4,5-c]pyridine-5(4H)-carboxylate 
• 40299-87-4 N-(bromoacetyl)morpholine 
• 845267-78-9 tert-butyl 2,4-dioxopiperidine-1-carboxylate 

Relevant articles and documents

Isoxazolodihydropyridinones: 1,3-dipolar cycloaddition of nitrile oxides onto 2,4-dioxopiperidines

Practical and efficient methods have been developed for the diversity-oriented synthesis of isoxazolodihydropyridinones via the 1,3-dipolar cycloaddition of nitrile oxides onto 2,4-dioxopiperidines. A select few of these isoxazolodihydropyridinones were further elaborated with triazoles by copper-catalyzed azide-alkyne cycloaddition reactions. A total of 70 compounds and intermediates were synthesized and analyzed for drug likeness. Sixty-four of these novel compounds were submitted to the NIH Molecular Libraries Small Molecule Repository for high-throughput biological screening.