1365998-30-6

Basic information

• Product Name: (S)-3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-1'-(5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl)-[1,4'-bipiperidin]-2-one
• Synonyms: (S)-3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-1'-(5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl)-[1,4'-bipiperidin]-2-one
• CAS NO: 1365998-30-6
• Molecular Weight: 520.505
• Mol File: 1365998-30-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-1'-(5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl)-[1,4'-bipiperidin]-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-1'-(5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl)-[1,4'-bipiperidin]-2-one(1365998-30-6)
• EPA Substance Registry System: (S)-3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-1'-(5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl)-[1,4'-bipiperidin]-2-one(1365998-30-6)

Safety Data

• Hazardous Substances Data: 1365998-30-6(Hazardous Substances Data)

Upstream product

• 1351167-99-1 (S)-3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-[1,4'-bipiperidin]-2-one 
• 1351168-02-9 (S)-tert-butyl 3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-2-oxo-1,4'-bipiperidin-1'-carboxylate 
• 1351168-01-8 (R)-tert-butyl 3-(methylsulfonyloxy)-2-oxo-1,4'-bipiperidin-1'-carboxylate 
• 1351168-00-7 (R)-tert-butyl 3-hydroxy-2-oxo-[1,4'-bipiperidin]-1'-carboxylate 
• 381-72-6 difluoroacetyl chloride 
• 1366298-53-4 (S,E)-3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-N'-hydroxy-2-oxo-1,4'-bipiperidine-1'-carboximidamide 

Relevant articles and documents

PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS

Compounds of Formula (I) and pharmaceutically acceptable salts thereof in which X1, X2, L, R3, R4, R5, R7 and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as such as, but not limited to, type 2 diabetes, diabetic complications, symptoms of diabetes, metabolic syndrome, obesity, dyslipidemia, and related conditions.