13678-69-8

Basic information

• Product Name: 1-(2-thienyl)propane-1,2-dione
• Synonyms: 1-(2-thienyl)propane-1,2-dione;EINECS 237-174-4;1-(2-Thienyl)-1,2-propanedione
• CAS NO: 13678-69-8
• Molecular Formula: C₇H₆O₂S
• Molecular Weight: 154.18634
• EINECS: 237-174-4
• Mol File: 13678-69-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 46-47 °C
• Boiling Point: 237.6 °C at 760 mmHg
• Flash Point: 97.5 °C
• Appearance: /
• Density: 1.242 g/cm³
• Vapor Pressure: 0.0445mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: 1-(2-thienyl)propane-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-thienyl)propane-1,2-dione(13678-69-8)
• EPA Substance Registry System: 1-(2-thienyl)propane-1,2-dione(13678-69-8)

Safety Data

• Hazardous Substances Data: 13678-69-8(Hazardous Substances Data)

Usage

General Description

1-(2-thienyl)propane-1,2-dione, also known as 2-thiopheneacetylacetone, is a chemical compound with the molecular formula C7H8O2S. It is a bright yellow, crystalline solid and is commonly used as a chelating agent in coordination chemistry. It has a strong chelating ability due to its thione sulfur and carbonyl oxygen atoms, which allows it to bind to metal ions in a variety of applications such as catalysis, metal extraction, and material science. The compound is also used as a precursor in the synthesis of pharmaceuticals and various organic compounds. Additionally, it has potential applications in the field of fluorescence sensing and fluorescent probes due to its unique properties. Overall, 1-(2-thienyl)propane-1,2-dione is a versatile chemical compound with a wide range of uses in various industries.

InChI:InChI=1/C7H6O2S/c1-5(8)7(9)6-3-2-4-10-6/h2-4H,1H3

Upstream product

• 3051-27-2 1-(2-thienyl)-1,3-butanedione 
• 1346260-46-5 (E)-2-(methoxyimino)-1-(thiophen-2-yl)propan-1-one 
• 96514-32-8 C₈H₇NOS 
• 15022-18-1 1-(thiophen-2-yl)propan-2-one 

Downstream Products

• 107486-55-5 2,5-Dimethyl-1-hydroxy-4-phenyl-2-(thenoyl-2)-3-imidazoline 3-oxide 

Relevant articles and documents

Copper-catalyzed TEMPO oxidative cleavage of 1,3-diketones and β-keto esters for the synthesis of 1,2-diketones and α-keto esters

A copper-catalyzed efficient and practical method has been developed for the synthesis of 1,2-diketones and α-keto esters. TEMPO was used as a radical initiator and scavenger, oxidizing the cleavage of α-methylene of 1,3-diketones and β-keto esters to form 1,2-diketones and α-keto esters. This method provided a general way for the formation of 1,2-dicarbonyl compounds.

Synthesis of 1,2-diketones from β-keto nitriles via a protection-oxidative-decyanation-deprotection protocol

A variety of 1,2-diketones were prepared from -keto nitriles via a three-step protocol including the protection of the ketones with methoxyamine, oxidative decyanation, and microwave-assisted deprotection in the final step. This approach provides a novel and efficient access to a wide scope of symmetric and unsymmetric 1,2-diketones using molecular oxygen as the oxidant in the decyanation process. Georg Thieme Verlag Stuttgart - New York.