1367905-79-0Relevant articles and documents
Visible-Light-Mediated Aerobic Oxidation of N-Alkylpyridinium Salts under Organic Photocatalysis
Jin, Yunhe,Ou, Lunyu,Yang, Haijun,Fu, Hua
, p. 14237 - 14243 (2017)
Quinolones and isoquinolones exhibit diverse biological and pharmaceutical activities, and their synthesis is highly desirable under mild conditions. Here, a highly efficient and environmentally friendly visible light-mediated aerobic oxidation of readily available N-alkylpyridinium salts has been developed with Eosin Y as the organic photocatalyst and air as the terminal oxidant, and the reaction provided quinolones and isoquinolones in good yields. The method shows numerous advantages including mild and environmentally friendly conditions, high efficiency, tolerance of wide functional groups and low cost. Furthermore, 4-desoxylonimide with important pharmaceutical activities was effectively prepared by using our method. Therefore, the present method should provide a novel and useful strategy for synthesis and modification of N-heterocycles.
PROCESS FOR PREPARING A COT INHIBITOR COMPOUND
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, (2021/10/11)
Disclosed are syntheses of a Cot (cancer Osaka thyroid) inhibitor, which has the formula (I).
CARBAZOLE COMPOUNDS AND METHODS OF USING SAME
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Paragraph 00115-00116, (2015/02/25)
The present invention provides carbazole compounds of the formula (I), which can be used for treating microbial, protozoan, viral infections and cancer. ?