136849-72-4 Usage
Description
TOTU, also known as 3-(Triethoxysilyl)propyl isocyanate, is a versatile reagent used in various chemical and pharmaceutical applications. It is a white to yellowish crystalline powder with unique chemical properties that make it suitable for a wide range of uses.
Uses
Used in Pharmaceutical Applications:
TOTU is used as a reagent for the Watson-Crick pairing of oligonucleotides, which is crucial in the development of new drugs and therapies.
Used in Nucleoside Synthesis:
TOTU is used as an agent for the esterification of nucleosides to solid phase supports, which is an essential step in the synthesis of nucleic acids and their derivatives.
Used in Integrin Antagonist Synthesis:
TOTU is used as a reagent in the synthesis of selective integrin avβ3 antagonists, which are important in the development of drugs targeting various diseases, including cancer.
Used in DNA Library Synthesis:
TOTU is used in the design and synthesis of double-stranded DNA libraries, which are vital for research in genomics and drug discovery.
Used in β-amino Acid Derivative Synthesis:
TOTU is used in the preparation of conformationally constrained β-amino acid derivatives, which are important building blocks in the development of new pharmaceuticals.
Used in Peptide Synthesis:
TOTU is used in the synthesis and application of methyleneoxy pseudopeptide building blocks, which are essential for the development of novel peptide-based drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 136849-72-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,8,4 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 136849-72:
(8*1)+(7*3)+(6*6)+(5*8)+(4*4)+(3*9)+(2*7)+(1*2)=164
164 % 10 = 4
So 136849-72-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H17N4O3.BF4/c1-6-16-9(15)8(7-11)12-17-10(13(2)3)14(4)5;2-1(3,4)5/h6H2,1-5H3;/q+1;-1/b12-8+;
