136881-87-3

Basic information

• Product Name: 3,5-Hexadiyn-2-ol, 6-(4-chlorophenyl)-2-methyl-
• CAS NO: 136881-87-3
• Molecular Formula: C13H11ClO
• Molecular Weight: 218.683
• Mol File: 136881-87-3.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 3,5-Hexadiyn-2-ol, 6-(4-chlorophenyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Hexadiyn-2-ol, 6-(4-chlorophenyl)-2-methyl-(136881-87-3)
• EPA Substance Registry System: 3,5-Hexadiyn-2-ol, 6-(4-chlorophenyl)-2-methyl-(136881-87-3)

Safety Data

• Hazardous Substances Data: 136881-87-3(Hazardous Substances Data)

Upstream product

• 873-73-4 4-n-chlorophenylacetylene 
• 2063-19-6 4-bromo-2-methylbut-3-yn-2-ol 
• 763-12-2 2-methyl-3,5-hexadiyn-2-ol 
• 637-87-6 1-Chloro-4-iodobenzene 
• 5929-72-6 2,7-dimethyl-octa-3,5-diyne-2,7-diol 
• 75373-70-5 1-(4-Chlorophenyl)-3-methyl-1-butyn-3-ol 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 106-39-8 bromochlorobenzene 
• 156661-13-1 C₁₂H₁₃ClSe 

Downstream Products

• 40133-23-1 2-(4-chlorophenyl)thiophene 
• 1403835-78-8 C₁₇H₂₁ClOS 
• 136881-89-5 1-<3-(N-tert-butylhydroxyamino)-4-chlorophenyl>-5-methyl-1,3-hexadiyn-5-ol tetrahydropyranyl ether 
• 136881-85-1 6-[3-(tert-Butyl-hydroxy-amino)-4-chloro-phenyl]-2-methyl-hexa-3,5-diyn-2-ol 
• 129541-88-4 1-<4-Chloro-3-(N-tert-butyl-N-oxylamino)phenyl>-1,3-butadiyne 
• 129541-86-2 1-<3-(N-tert-butylhydroxyamino)-4-chlorophenyl>-1,3-butadiyne 
• 136881-88-4 1-(p-chlorophenyl)-5-methyl-1,3-hexadiyn-5-ol tetrahydropyranyl ether 
• 131292-29-0 6-(4-chlorophenyl)-2-methylhexa-3,5-diyn-2-ol 

Relevant articles and documents

Design and synthesis of new 5-aryl-4-arylethynyl-1H-1,2,3-triazoles with valuable photophysical and biological properties

Cu-catalyzed 1,3-dipolar cycloaddition of methyl 2-azidoacetate to iodobuta-1,3-diynes and subsequent Suzuki-Miyaura cross-coupling were used to synthesize new triazoles derivatives: 5aryl-4-arylethynyl-1H-1,2,3-triazoles. Investigation of their optical p

Tuning of cross-Glaser products mediated by substrate-catalyst polymeric backbone interactions

Tuning of cross-Glaser products using different polymeric backbones supported by copper oxide nano-catalysts has been demonstrated by tweaking the substrate-catalyst interactions under greener conditions. Further, highly reactive magnetically separable and recyclable catalyst with scalability is demonstrated.

One-pot synthesis of unsymmetrical 1,3-butadiyne derivatives and their application in the synthesis of unsymmetrical 2,5-diarylthiophenes

A one-pot protocol was developed for the synthesis of unsymmetrical 1,3-butadiynes. The procedure is based on two sequential reactions: deprotection of R–C≡C–C≡C– C(Me)2OH derivatives in a retro-Favorskii reaction to furnish a terminal 1,3-butadiyne compound, which reacted with aryl iod-ides in a Sonogashira-type cross-coupling reaction catalyzed by Pd(PPh3)4 and CuI, using TBAOH as activator and toluene as solvent under reflux for 10 min. We also studied in situ thiocycli-zation of 1,3-butadiynes, leading to unsymmetrical 2,5-diaryl-thiophenes. The principal features of this method are operational simplicity, good substrate scope, very fast reaction, and high yields.