136906-08-6Relevant articles and documents
Centrally acting 6,7,8,9-tetrahydro-3H-benz(E)indole heterocyclics
-
, (2008/06/13)
A compound of Formula I STR1 or pharmaceutically acceptable salts of Formula I, where R1 is H, C1 -C3 alkyl, --(CH2)n CONH2 where n is 2 to 6, (CH2)n -1-(4,4-dimethylpiperidine-2
Synthesis of (R)- and (S)-1-formyl-6,7,8,9-tetrahydro-N,N-(dipropyl)-3H- benz[e]indol-8-amines: Potent and orally active 5-HT(1A) receptor agonists
Lin,Ennis,Hoffman,Phillips,Haadsma-Svensson,Ghazal,Chidester
, p. 129 - 139 (2007/10/02)
An efficient synthesis of the potent and orally active 5-HT(1A) agonists, (R)-(+)- and (S)-(-)-l-formyl-6,7,8,9-tetrahydro-N,N-dipropyl-3H- benz[e]indol-8-amines 1a and 1b, is described. This synthesis was accomplished in twelve steps from commercially av