1369542-55-1

Basic information

• Product Name: rac-N-[3-(6-amino-4-methyl-4,7-dihydropyrazolo[1,5-a]pyrazin-4-yl)-phenyl]-5-chloropyridine-2-carboxamide
• Synonyms: rac-N-[3-(6-amino-4-methyl-4,7-dihydropyrazolo[1,5-a]pyrazin-4-yl)-phenyl]-5-chloropyridine-2-carboxamide
• CAS NO: 1369542-55-1
• Molecular Weight: 380.837
• Mol File: 1369542-55-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: rac-N-[3-(6-amino-4-methyl-4,7-dihydropyrazolo[1,5-a]pyrazin-4-yl)-phenyl]-5-chloropyridine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: rac-N-[3-(6-amino-4-methyl-4,7-dihydropyrazolo[1,5-a]pyrazin-4-yl)-phenyl]-5-chloropyridine-2-carboxamide(1369542-55-1)
• EPA Substance Registry System: rac-N-[3-(6-amino-4-methyl-4,7-dihydropyrazolo[1,5-a]pyrazin-4-yl)-phenyl]-5-chloropyridine-2-carboxamide(1369542-55-1)

Safety Data

• Hazardous Substances Data: 1369542-55-1(Hazardous Substances Data)

Upstream product

• 1369543-06-5 rac-4-[3-((benzhydrylidene)amino)-phenyl]-4-methyl-4,7-dihydropyrazolo[1,5-a]pyrazin-6-amine 
• 1369543-05-4 rac-4-(3-bromophenyl)-4-methyl-4,7-dihydro-pyrazolo[1,5-a]pyrazin-6-amine 
• 1369543-04-3 rac-4-(3-bromophenyl)-4-methyl-1-4,5-dihydro-pyrazolo[1,5-a]pyrazine-6-thione 
• 1369543-02-1 rac-4-(3-bromophenyl)-4-methyl-4,5-dihydro-pyrazolo[1,5-a]pyrazin-6-one 
• 1369542-99-3 rac-N-[1-(3-bromophenyl)-1-(1H-pyrazol-3-yl)ethyl]-2-chloro-acetamide 
• 1369542-98-2 rac-1-(3-bromophenyl)-1-(1H-pyrazol-3-yl)ethanamine 
• 1369542-97-1 rac-tert-butyl N-[1-(3-bromophenyl)-1-(1H-pyrazol-3-yl)ethyl]carbamate 
• 1369542-96-0 rac-tert-butyl N-[1-(3-bromophenyl)-1-methyl-2-oxo-but-3-ynyl]carbamate 
• 1369542-95-9 rac-tert-butyl N-[1-(3-bromophenyl)-2-hydroxy-1-methyl-but-3-ynyl]carbamate 
• 887913-44-2 rac-[1-(3-bromo-phenyl)-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 887913-69-1 rac-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-carbamic acid tert-butyl ester 
• 1183013-69-5 (RS)-2-amino-2-(3-bromo-phenyl)-propan-1-ol 
• 1183581-39-6 (RS)-2-amino-2-(3-bromo-phenyl)-propionic acid methyl ester 
• 953741-63-4 rac-2-amino-2-(3-bromo-phenyl)-propionitrile 

Relevant articles and documents

4,7-DIHYDRO-PYRAZOLO[1,5-a]PYRAZIN-6-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)

The present invention relates to novel 4,7-dihydro-pyrazolo[1,5-a]pyrazin-6-yl-amine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease or dementia associated with beta-amyloid.