1369922-85-9

Basic information

• Product Name: phenyl 4,4,4-trifluoro-3-hydroxy-3-(thiophen-2-yl)butanoate
• Synonyms: phenyl 4,4,4-trifluoro-3-hydroxy-3-(thiophen-2-yl)butanoate
• CAS NO: 1369922-85-9
• Molecular Weight: 316.301
• Mol File: 1369922-85-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: phenyl 4,4,4-trifluoro-3-hydroxy-3-(thiophen-2-yl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl 4,4,4-trifluoro-3-hydroxy-3-(thiophen-2-yl)butanoate(1369922-85-9)
• EPA Substance Registry System: phenyl 4,4,4-trifluoro-3-hydroxy-3-(thiophen-2-yl)butanoate(1369922-85-9)

Safety Data

• Hazardous Substances Data: 1369922-85-9(Hazardous Substances Data)

Upstream product

• 651-70-7 2,2,2-trifluoro-1-(thiophen-2-yl)ethan-1-one 
• 35756-54-8 malonic acid monophenyl ester 

Relevant articles and documents

Convenient and efficient decarboxylative aldol reaction of malonic acid half esters with trifluoromethyl ketones

A convenient and efficient decarboxylative ketone aldol condensation of malonic acid half esters was reported. In the presence of catalytic amount of triethylamine, a series of aromatic and alkyl trifluoromethyl ketones were transformed into the desired adducts in 61-99% yields. In a preliminary experiment, a moderate stereoselectivity was obtained. Direct reduction of the aldol product with LiAlH4 afforded trifluoromethylated 1,3-diol.