137019-95-5

Basic information

• Product Name: 3,4,5-Trifluoro-4'-(trans-4-pentylcyclohexyl)biphenyl
• Synonyms: 3,4,5-Trifluoro-4'-(trans-4-pentylcyclohexyl)biphenyl;4''-(TRANS-4-PENTYLCYCLOHEXYL)-3,4,5-TRIFLUORO-BIPHENYL;3,4,5-Trifluoro-4`-(4-pentyl-cyclohexyl)biphenyl;3,4,5-Trifluoro-4'-(trans-4-pentylcyclohexyl)- 1,1'-biphenyl;[3,4,5-trifluoro-4-(4-pentylcyclohexyl)cyclohexa-1,5-dien-1-yl]benzene;trans-3,4,5-Trifluoro-4'-(4-n-pentylcyclohexyl)biphenyl, 99%;3,4,5-Trifluoro-4'-((1s,4r)-4-pentylcyclohexyl)biphenyl
• CAS NO: 137019-95-5
• Molecular Formula: C23H28F2
• Molecular Weight: 360.46
• Mol File: 137019-95-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 429.9 °C at 760 mmHg
• Flash Point: 248.4 °C
• Appearance: /
• Density: 1.073 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3,4,5-Trifluoro-4'-(trans-4-pentylcyclohexyl)biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-Trifluoro-4'-(trans-4-pentylcyclohexyl)biphenyl(137019-95-5)
• EPA Substance Registry System: 3,4,5-Trifluoro-4'-(trans-4-pentylcyclohexyl)biphenyl(137019-95-5)

Safety Data

• Hazardous Substances Data: 137019-95-5(Hazardous Substances Data)

Usage

Chemical Properties

White crystal

Uses

It is used as a medical intermediate.

Upstream product

• 79832-89-6 1-bromo-4-(trans-4-pentylcyclohexyl)benzene 
• 143418-49-9 3,4,5-trifluorophenylboronic acid 
• 138526-69-9 3,4,5-trifluoro-1-bromobenzene 
• 153873-83-7 1-bromo-4-(4-pentylcyclohexyl)benzene 
• 170112-66-0 1,2,3-trifluoro-5-iodobenzene 
• 948553-20-6 1-iodo-4-(4-pentylcyclohexyl)benzene 

Relevant articles and documents

Metallomicelles of palladium(II) complexes as efficient catalysts for the Suzuki-Miyaura reaction in neat water

Metallomicelles of palladium(II) complex 4 are found to be an efficient catalyst for Suzuki-Miyaura reactions of aryl bromides substituted with a long alkyl chain and arylboronic acids at 80 °C in neat water. The reactions proceed smoothly to generate the corresponding biaryl compounds in moderate to excellent yields. Various biphenyl derivatives were successfully obtained by complex 4 catalysis of the Suzuki-Miyaura reactions in the absence of any surfactants in neat water. Copyright

Nickel- and Palladium-Catalyzed Cross-Coupling of Stibines with Organic Halides: Site-Selective Sequential Reactions with Polyhalogenated Arenes

Herein, we disclose a general and efficient method for the synthesis of Sb-aryl and Sb-alkyl stibines by the nickel-catalyzed cross-coupling of halostibines with organic halides. The synthesized Sb-aryl stibines couple with aryl halides to give biaryls efficiently via palladium catalysis. Sequential reactions of stibines with polyhalogenated arenes bearing active C–I/C–Br sites and inactive C–Cl sites successfully proceeded, resulting in the formation of a variety of complex molecules with good site selectivity. Drugs such as diflunisal and fenbufen, as well as a fenofibrate derivative, were synthesized on gram scales in good yields, together with the high recovery of chlorostibine. Furthermore, catalytic mechanisms are proposed based on the results of control experiments.

Salen and half-salen palladium(II) complexes: synthesis, characteriztion and catalytic activity toward Suzuki-Miyaura reaction

Salen and half-salen palladium(II) complexes (salden)Pd (1, salden=N,N′-bis(3,5-di- tert-butylsalicylidene)-1,2-dimethylethylenediamine), (hsalph)PdCl (2, hsalph=3,5-di-tert- butylsalicylidene-1-iminophenylene-2-amine), and (salph)Pd (4, salph=N,N′-bis(3,