1370320-04-9

Basic information

• Product Name: (+)-tert-butyl N-[(1R,4S)-2-bromo-4-[(tert-butyldimethylsilyl)oxy]cyclohex-2-en-1-yl]carbamate
• Synonyms: (+)-tert-butyl N-[(1R,4S)-2-bromo-4-[(tert-butyldimethylsilyl)oxy]cyclohex-2-en-1-yl]carbamate
• CAS NO: 1370320-04-9
• Molecular Weight: 406.435
• Mol File: 1370320-04-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-tert-butyl N-[(1R,4S)-2-bromo-4-[(tert-butyldimethylsilyl)oxy]cyclohex-2-en-1-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-tert-butyl N-[(1R,4S)-2-bromo-4-[(tert-butyldimethylsilyl)oxy]cyclohex-2-en-1-yl]carbamate(1370320-04-9)
• EPA Substance Registry System: (+)-tert-butyl N-[(1R,4S)-2-bromo-4-[(tert-butyldimethylsilyl)oxy]cyclohex-2-en-1-yl]carbamate(1370320-04-9)

Safety Data

• Hazardous Substances Data: 1370320-04-9(Hazardous Substances Data)

Upstream product

• 1370320-03-8 C₁₃H₂₄BrNO₃Si 
• 75-65-0 tert-butyl alcohol 
• 174817-06-2 cis-(1S,2S)-1,2-dihydroxy-3-bromocyclohex-3-ene 
• 108-86-1 bromobenzene 
• 67451-62-1 cis-(1S,2S)-1,2-dihydroxy-3-bromocyclohexa-3,5-diene 

Downstream Products

• 1370320-05-0 (+)-tert-butyl N-[(1R,4S)-4-[(tert-butyldimethylsilyl)oxy]-2-(6-chloropyridin-3-yl)cyclohex-2-en-1-yl]carbamate 
• 1370320-06-1 (+)-tert-butyl N-[(1R,4S)-2-(6-chloropyridin-3-yl)-4-hydroxycyclohex-2-en-1-yl]carbamate 
• 211503-91-2 (-)-tert-butyl N-[(1R,2R,4S)-2-(6-chloropyridin-3-yl)-4-hydroxycyclohexyl]carbamate 
• 211503-92-3 N-[(1R,2R,4R)-4-bromo-2-(6-chloro(3-pyridyl))cyclohexyl](tert-butoxy)carboxamide 
• 217323-82-5 (1R,2R,4R)-4-bromo-2-(6-chloropyridin-3-yl)cyclohexanamine 
• 1370320-08-3 (+)-tert-butyl (1R,4S)-2-bromo-4-hydroxycyclohex-2-enylcarbamate 
• 455330-42-4 4R-(4-oxocyclohex-2-enyl)carbamic acid tert-butyl ester 

Relevant articles and documents

Chemoenzymatic formal synthesis of (-)- and (+)-epibatidine

The cis-dihydrocatechol, derived from enzymatic cis-dihydroxylation of bromobenzene using the microorganism Pseudomonas putida UV4, was converted into (-)-epibatidine in eleven steps with complete stereocontrol. In addition, an unprecedented palladium-catalysed disproportionation reaction gave the (+)-enantiomer of an advanced key intermediate employed in a previous synthesis of epibatidine.