13704-45-5Relevant articles and documents
A new method using 2-chloro-4,6-dimethoxy-1,3,5-triazine for facile elimination of dimethylamino group in Eschenmoser's methylenation for synthesis of α,β-unsaturated esters
Yamada, Kohei,Masaki, Kazumasa,Hagimoto, Yuri,Kamiya, Seina,Kunishima, Munetaka
, p. 1758 - 1760 (2013/03/29)
A facile one-step method for the elimination of the dimethylamino group in Eschenmoser's methylenation has been developed using a combination of 2-chloro-4,6-dimethoxy-1,3,5-triazine and triethylamine. The chemoselective elimination of the dimethylamino group occurred in compounds possessing either a diethylamino group or an alkylsulfanyl group.