1370522-66-9

Basic information

• Product Name: 5-Hydroxy-7-(3,4-dimethoxyphenyl)-2-phenyl-4H-chromen-4-one
• Synonyms: 5-Hydroxy-7-(3,4-dimethoxyphenyl)-2-phenyl-4H-chromen-4-one
• CAS NO: 1370522-66-9
• Molecular Weight: 374.393
• Mol File: 1370522-66-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Hydroxy-7-(3,4-dimethoxyphenyl)-2-phenyl-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hydroxy-7-(3,4-dimethoxyphenyl)-2-phenyl-4H-chromen-4-one(1370522-66-9)
• EPA Substance Registry System: 5-Hydroxy-7-(3,4-dimethoxyphenyl)-2-phenyl-4H-chromen-4-one(1370522-66-9)

Safety Data

• Hazardous Substances Data: 1370522-66-9(Hazardous Substances Data)

Upstream product

• 122775-35-3 3,4-Dimethoxyphenylboronic acid 
• 109586-45-0 trifluoromethanesulfonic acid 5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl ester 
• 480-40-0 5,7-dihydroxy-2-phenyl-chromen-4-one 

Relevant articles and documents

Efficient synthesis of arylated flavones by site-selective Suzuki-Miyaura cross-coupling reactions of the bis(triflate) of 5,7- and 7,8-dihydroxyflavone

Suzuki-Miyaura reactions of the bis(triflate) of 5,7- and 7,8-dihydroxyflavone proceed with very good site selectivity in favor of position 7 and allow the synthesis of various arylated flavones. The reaction of 5,7-dihydroxyflavone with one equivalent of triflic anhydride also proceeds with very good site selectivity in favor of position 7. The subsequent Suzuki-Miyaura reaction of the product allows the synthesis of 7-aryl-5-hydroxyflavones. The regioselectivity is discussed based on DFT calculations.