1370593-41-1

Basic information

• Product Name: (2-allyl-3,4-dimethoxy-phenyl)-O-tolyl-methanone
• Synonyms: (2-allyl-3,4-dimethoxy-phenyl)-O-tolyl-methanone
• CAS NO: 1370593-41-1
• Molecular Weight: 296.366
• Mol File: 1370593-41-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2-allyl-3,4-dimethoxy-phenyl)-O-tolyl-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-allyl-3,4-dimethoxy-phenyl)-O-tolyl-methanone(1370593-41-1)
• EPA Substance Registry System: (2-allyl-3,4-dimethoxy-phenyl)-O-tolyl-methanone(1370593-41-1)

Safety Data

• Hazardous Substances Data: 1370593-41-1(Hazardous Substances Data)

Upstream product

• 932-31-0 ortho-tolylmagnesium bromide 
• 92345-90-9 3,4-dimethoxy-2-allylbenzaldehyde 
• 18075-40-6 O-allylisovanillin 
• 18075-41-7 2-allyl-3-hydroxy-4-methoxybenzaldehyde 
• 621-59-0 isovanillin 

Downstream Products

• 143576-58-3 5,6-dimethoxy-1-O-tolyl-isoquinoline 
• 1420805-25-9 1-(2,3-dimethoxy-6-(2-methylbenzoyl)phenyl)propan-2-one 
• 1420804-99-4 7,8-dimethoxy-4-o-tolylnaphthalen-2-ol 

Relevant articles and documents

CuI Mediated One-Pot Cycloacetalization/Ketalization of o-Carbonyl Allylbenzenes: Synthesis of Benzobicyclo[3.2.1]octane Core

CuI/DMSO-mediated intramolecular cycloacetalization/ketalization of o-carbonyl allylbenzenes has been achieved for constructing [6,6,5]-tricycles having a ketal motif in good yields. The expeditious one-step route provides a three C-O bond formation. The key products with the structural framework of a benzofused dioxabicyclo[3.2.1]octane core have been confirmed by X-ray crystallographic analysis. Synthesis of dihydroisocoumarin has been studied.

One-pot access to 2-naphthols and benzofurans via the aerobic Wacker-type oxidation/intramolecular aldol cyclization

An aerobic Wacker-type oxidation/intramolecular aldol cyclization synthetic route toward two oxygenated 2-naphthols 3 and benzofurans 4 starting with skeleton 2 with good yields is described. The route has been carried by the one-pot transformation of the regioselective PdCl2/CuCl 2-mediated Wacker oxidative cyclization of skeleton 2 with molecular oxygen under the alkaline methanolic condition. Skeleton 2 was prepared from skeleton 1 in moderate total yields via the known protocol.