137174-05-1Relevant articles and documents
A highly stereoselective divergent synthesis of bicyclic models of photoreactive sesquiterpene lactones
Fuchs, Sebastien,Berl, Valerie,Lepoittevin, Jean-Pierre
, p. 1145 - 1152 (2008/02/06)
Sesquiterpene lactones are natural stereochemically pure compounds, which show a number of biological activities. In order to study the reactivity of sesquiterpene lactones in biological systems, we describe herein the asymmetric synthesis of a simple mod
Synthesis of enantiomerically pure (-)-wine lactone based on a palladium-catalyzed enantioselective allylic substitution
Bergner,Helmchen, Guenter
, p. 419 - 423 (2007/10/03)
The first enantioselective synthesis of enantiomerically pure (-)-wine lactone, (-)-1a, a fragrance constituent of various white wines, and its epimer (+)-1b, was carried out. The key steps are allylic substitution of (±)-2-cyclohexen-1-yl acetate (2) wit
Asymmetric Catalysis by Vitamin B12: The Isomerization of Achiral Cyclopropanes to Optically Active Olefins
Troxler, Thomas,Scheffold, Rolf
, p. 1193 - 1202 (2007/10/02)
Achiral spiroactivated cyclopropanes are isomerized to optically active (R)-(cycloalk-2-enyl)-Meldrum's acids (= (R)-5-(cycloalk-2-enyl)-2,2-dimethyl-1,3-dioxane-4,6-diones) in high yield and ee's up to 86percent by catalytic amounts of cob(I)alamin in po