1372527-86-0Relevant articles and documents
Novel compounds containing multiple guanide groups that bind the HIV coreceptor CXCR4
Wilkinson, Royce A.,Pincus, Seth H.,Shepard, Joyce B.,Walton, Sarah K.,Bergin, Edward P.,Labib, Mohamed,Teintze, Martin
, p. 255 - 263 (2011/12/15)
The G-protein-coupled receptor CXCR4 acts as a coreceptor for human immunodeficiency virus type 1 (HIV-1) infection, as well as being involved in signaling cell migration and proliferation. Compounds that block CXCR4 interactions have potential uses as HI