1372616-50-6

Basic information

• Product Name: C₁₆H₈F₄S
• Synonyms: C₁₆H₈F₄S
• CAS NO: 1372616-50-6
• Molecular Weight: 308.299
• Mol File: 1372616-50-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₆H₈F₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₈F₄S(1372616-50-6)
• EPA Substance Registry System: C₁₆H₈F₄S(1372616-50-6)

Safety Data

• Hazardous Substances Data: 1372616-50-6(Hazardous Substances Data)

Upstream product

• 1109-15-5 tris(pentafluorophenyl)borate 
• 91-60-1 2-Naphthalenethiol 
• 363-72-4 Pentafluorobenzene 
• 831-23-2 S-naphthalen-2-yl thioacetate 

Relevant articles and documents

Synthesis of polyfluorinated aromatic ethers and thioethers by synergistic cleavage of C-B bond and C-F bond of B(C6F5)3

A concise and efficient method for the synthesis of polyfluorinated aromatic ethers and thioethers by synergistic cleavage of C-B bond and C-F bond of B(C6F5)3 is reported. The reaction could proceed smoothly with excellent functional-group compatibility. In addition, the transformation represents the first general application of B(C6F5)3 as reaction partners in cross-coupling reaction.

Regioselective C-S bond formation accomplished by copper-catalyzed regioselective C-F substitution of perfluoroarenes with aryl thioacetates or benzyl thioacetate

Practical and straightforward method for regioselective C-S bond formation accomplished by copper-catalyzed regioselective C-F substitution of electron-deficient perfluoroarenes with aryl thioacetates or benzyl thioacetate has been developed. Because of its high reaction efficiency, good chemoselectivity and regioselectivity, and excellent functional-group compatibility, this protocol provides a useful and operationally simple access to polyfluoroaryl thioethers used for drugs and material chemistry.