137267-44-8

Basic information

• Product Name: 4-Thiazolecarboxylicacid,2,5-dimethyl-,ethylester(9CI)
• Synonyms: 4-Thiazolecarboxylicacid,2,5-dimethyl-,ethylester(9CI);ethyl 2,5-dimethyl-1,3-thiazole-4-carboxylate
• CAS NO: 137267-44-8
• Molecular Formula: C₈H₁₁NO₂S
• Molecular Weight: 185.25
• Product Categories: THIAZOLE
• Mol File: 137267-44-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 254.3±20.0 °C(Predicted)
• Appearance: /
• Density: 1.164±0.06 g/cm3(Predicted)
• PKA: 1.58±0.10(Predicted)
• CAS DataBase Reference: 4-Thiazolecarboxylicacid,2,5-dimethyl-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolecarboxylicacid,2,5-dimethyl-,ethylester(9CI)(137267-44-8)
• EPA Substance Registry System: 4-Thiazolecarboxylicacid,2,5-dimethyl-,ethylester(9CI)(137267-44-8)

Safety Data

• Hazardous Substances Data: 137267-44-8(Hazardous Substances Data)

Upstream product

• 57332-84-0 3-bromo-2-oxo-butyric acid ethyl ester 
• 62-55-5 thioacetamide 

Downstream Products

• 113366-73-7 2,5-dimethyl-1,3-thiazole-4-carboxylic acid 
• 113366-74-8 5-ethyl-2-methylthiazole-4-carboxylic acid 
• 113366-67-9 N,N-diethyl-5-(2-hydroxy-2-phenylethyl)-2-methylthiazole-4-carboxamide 
• 113366-68-0 N,N-diethyl-5-(2-hydroxy-2-phenylpropyl)-2-methylthiazole-4-carboxamide 

Relevant articles and documents

Regioselectivity in the Lithiation of Methyl-substituted Thiazole- and Oxazole-Carboxylic Acids and Carboxamides: General Methods for the Elaboration of Trisubstituted Thiazoles and Oxazoles

A number of anionic intermediates have been developed which are suitable for the elaboration of trisubstituted thiazoles and oxazoles.Thus, deprotonation of 2,4-dimethylthiazole-5-carboxylic acid 9 using either BuLi or LDA occurs regiospecifically at the