137269-68-2

Basic information

• Product Name: 1-[5-amino-3-(4-methylpiperazinyl)-1H-1,2,4-triazol-1-yl]-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}carbothioamide
• CAS NO: 137269-68-2
• Molecular Weight: 472.658
• Mol File: 137269-68-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[5-amino-3-(4-methylpiperazinyl)-1H-1,2,4-triazol-1-yl]-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}carbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[5-amino-3-(4-methylpiperazinyl)-1H-1,2,4-triazol-1-yl]-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}carbothioamide(137269-68-2)
• EPA Substance Registry System: 1-[5-amino-3-(4-methylpiperazinyl)-1H-1,2,4-triazol-1-yl]-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}carbothioamide(137269-68-2)

Safety Data

• Hazardous Substances Data: 137269-68-2(Hazardous Substances Data)

Upstream product

• 73278-98-5 N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>amine 
• 131023-08-0 methyl <5-amino-3-(4-methylpiperazino)-1,2,4-triazol-1-yl>dithiocarbonate 
• 73279-29-5 N-3-[3-(1-piperidinomethyl)phenoxy]propyl isothiocyanate 
• 89292-91-1 5-amino-2-(4-methyl-1-piperazinyl)-1H-1,2,4-triazole 

Relevant articles and documents

Triazolyl thioamide derivates

The invention relates to novel triazolyl thioamides of the general formula (I), STR1 wherein Q represents hydrogen or a heterocyclic group optionally bearing one or more C1-4 alkyl substituent(s), or a group of the formula SR1, wherein R1 stands for straight or branched chained alkyl group comprising 1 to 6 carbon atom(s), or a group of the formula NR2 R3, wherein R2 and R3 each represent hydrogen, straight or branched chained C1-4 alkyl or C2-6 alkenyl group, Y denotes C1-4 alkyl optionally bearing one or more hydroxyl or C1-4 alkoxy substituent(s), phenyl-(C1-4 alkyl) optionally bearing on the phenyl ring one or more C1-4 alkoxy group(s), or phenoxy-(C1-4 alkyl) optionally substituted on the phenyl ring by a C1-4 alkyl bearing a heterocyclic group containing a nitrogen atom, and pharmaceutically acceptable acid addition salts thereof. Furthermore the invention relates to a process for preparing these compounds. The compounds according to the invention possess tranquillant, antidepressant, spacmolytic, antiinflammatory, analgesic and antiperistaltic effects.