1373156-52-5Relevant articles and documents
Discovery of novel and potent heterocyclic carboxylic acid derivatives as protein tyrosine phosphatase 1B inhibitors
Basu, Sujay,Prasad, Uppuleti Viplava,Barawkar, Dinesh A.,De, Siddhartha,Palle, Venkata P.,Menon, Suraj,Patel, Meena,Thorat, Sachin,Singh, Umesh P.,Sarma, Koushik Das,Waman, Yogesh,Niranjan, Sanjay,Pathade, Vishal,Gaur, Ashwani,Reddy, Satyanarayana,Ansari, Shariq
, p. 2843 - 2849 (2012/05/20)
A series of novel heterocyclic carboxylic acid based protein tyrosine phosphatase 1B (PTP1B) inhibitors with hydrophobic tail have been synthesized and characterized. Structure-activity relationship (SAR) optimization resulted in identification of several