1373350-61-8

Basic information

• Product Name: 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate
• Synonyms: 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate
• CAS NO: 1373350-61-8
• Molecular Formula: C24H25ClFNO7S
• Molecular Weight: 525.9742032
• Product Categories: Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 1373350-61-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate(1373350-61-8)
• EPA Substance Registry System: 5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate(1373350-61-8)

Safety Data

• Hazardous Substances Data: 1373350-61-8(Hazardous Substances Data)

Usage

Description

5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate is a chemical compound with a complex structure, characterized by its unique arrangement of atoms and functional groups. It is an impurity found in Prasugrel, a medication used to prevent blood clots.

Uses

Used in Pharmaceutical Industry:
5-(5-Chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl Acetate Maleate is used as an impurity in the production of Prasugrel (P701150) for the purpose of ensuring the quality and safety of the final drug product. As an impurity, it is crucial to monitor and control its levels to maintain the efficacy and safety profile of Prasugrel.

InChI:InChI=1S/C20H21ClFNO3S/c1-13(24)26-19-11-15-12-23(9-7-18(15)27-19)20(17(25)6-3-8-21)14-4-2-5-16(22)10-14/h2,4-5,10-11,20H,3,6-9,12H2,1H3

Upstream product

• 1056459-35-8 5-chloro-1-(2-fluorophenyl)-pentan-2-one 
• 109904-26-9 5-triphenylmethyl-2-oxo-2,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridine 
• 109904-25-8 N-trityl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine 
• 150322-73-9 1-cyclopropyl-2-(2-fluorophenyl)ethanone 
• 28783-41-7 6,7-dihydro-4H-thieno[3,2-c]pyridine hydrochloride 
• 1056459-37-0 2-acetoxy-5-[5-chloro-1-(2-fluorophenyl)-2-oxopentyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine 
• 6915-18-0 2-butenedioic acid 

Relevant articles and documents

METHOD FOR PREPARING PHARMACEUTICALLY ACTIVE INGREDIENT AND INTERMEDIATES THEREOF

The present invention is related to a safe and industrially applicable method for the preparation of 2-acetoxy-5-(2-fluoro-α-cyclopropyl- carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-thieno[3,2-c]pyridine in a quality suitable for use as pharmaceutically active ingredient wherein the concentration of the impurities of the Formula.(XXIV) or (XXIVa) is reduced.