1373501-84-8Relevant articles and documents
Ugi reaction-assisted rapid assembly of affinity-based probes against potential protein tyrosine phosphatases
Ge, Jingyan,Cheng, Xiamin,Tan, Lay Pheng,Yao, Shao Q.
, p. 4453 - 4455 (2012/05/20)
The multi-component Ugi reaction has been employed to assemble a small library of affinity-based probes (AfBPs) that target potential protein tyrosine phosphatases. The probes showed good labelling of PTP1B and MptpB, and were subsequently used to label endogenous PTP1B in MCF-7 cell lysates.