1373758-48-5

Basic information

• Product Name: 5-(4-ethoxyphenyl)-2-phenyloxazole
• Synonyms: 5-(4-ethoxyphenyl)-2-phenyloxazole
• CAS NO: 1373758-48-5
• Molecular Weight: 265.312
• Mol File: 1373758-48-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-(4-ethoxyphenyl)-2-phenyloxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-ethoxyphenyl)-2-phenyloxazole(1373758-48-5)
• EPA Substance Registry System: 5-(4-ethoxyphenyl)-2-phenyloxazole(1373758-48-5)

Safety Data

• Hazardous Substances Data: 1373758-48-5(Hazardous Substances Data)

Upstream product

• 2835-06-5 phenylglycin 
• 79887-14-2 4-ethoxyphenylacetylene 
• 1676-63-7 4'-ethoxyacetophenone 
• 100-46-9 benzylamine 
• 433229-42-6 2-(4-methoxyphenyl)acetaldehyde 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 

Relevant articles and documents

Synthesis of 2,5-Disubstituted Oxazoles from Arylacetylenes and α-Amino Acids through an i 2 /Cu(NO 3) 2 ?3H 2 O-Assisted Domino Sequence

A new strategy has been developed for the synthesis of 2,5-disubstituted oxazoles from easily available arylacetylenes and α-amino acids in the presence of Cu(NO 3) 2 ?3H 2 O and iodine. This reaction process involves the I 2 /Cu(NO 3) 2 ?3H 2 O-assisted transformation of arylacetylene to α-iodo acetophenone, Kornblum oxidation to phenylglyoxal, condensation to imine, decarboxylation/annulation/oxidation reaction sequence to approach 2,5-disubstituted oxazoles.

Synthesis of 2,5-disubstituted oxazoles and oxazolines catalyzed by ruthenium(II) porphyrin and simple copper salts

A novel and moderate synthesis of 2,5-disubstituted oxazoles and oxazolines involving ruthenium(II) porphyrin-copper chloride catalyzed cyclization was developed. These reactions using readily available benzene carboxylic acids and phenylethenes or phenylacetylenes are performed under mild conditions. The reactions proceed in series, giving rise to the formation of an intermolecular C-N bond and an intramolecular C-O bond, which yield oxazole or oxazoline derivatives simultaneously.