1373763-18-8

Basic information

• Product Name: C₁₇H₁₂ClFN₂O₂S
• Synonyms: C₁₇H₁₂ClFN₂O₂S
• CAS NO: 1373763-18-8
• Molecular Weight: 362.812
• Mol File: 1373763-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₂ClFN₂O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₂ClFN₂O₂S(1373763-18-8)
• EPA Substance Registry System: C₁₇H₁₂ClFN₂O₂S(1373763-18-8)

Safety Data

• Hazardous Substances Data: 1373763-18-8(Hazardous Substances Data)

Upstream product

• 317-20-4 7-fluoro-1H-indole-2,3-dione 
• 108-42-9 3-chloro-aniline 
• 107-96-0 3-mercaptopropionic acid 

Relevant articles and documents

Br?nsted acidic ionic liquids: Green, efficient and reusable catalyst for synthesis of fluorinated spiro [indole-thiazinones/thiazolidinones] as antihistamic agents

Br?nsted acidic ionic liquid containing nitrogen-based organic cations 1-methylimidazolium and 1-butyl-3-methylimidazolium and inorganic anions such as BF4-, PF6- and PTSA - used as catalysts and reaction medium for synthesis of fluorinated spiro[3H-indole-3,2′-tetrahydro-1,3-thiazine]-2,4′(1H)-diones (4a-f), fluorinated spiro[3H-indole-3,2′-thiazolidine]-2,4′ (1H)-diones (5a-f) in 90-97% yield by one-pot environmentally benign microwave induced technique. Synthesized compounds have been evaluated for their ability to inhibit the contractions induced by histamine on guinea pig ileum. The measurement of pA2 values suggested that the reported compounds showed H1-antagonism.