1373919-59-5

Basic information

• Product Name: (R)-3-(hydroxymethyl)isobenzofuran-1(3H)-one
• Synonyms: (R)-3-(hydroxymethyl)isobenzofuran-1(3H)-one
• CAS NO: 1373919-59-5
• Molecular Weight: 164.161
• Mol File: 1373919-59-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-(hydroxymethyl)isobenzofuran-1(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(hydroxymethyl)isobenzofuran-1(3H)-one(1373919-59-5)
• EPA Substance Registry System: (R)-3-(hydroxymethyl)isobenzofuran-1(3H)-one(1373919-59-5)

Safety Data

• Hazardous Substances Data: 1373919-59-5(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 34560-28-6 2-vinylbenzonitrile 

Relevant articles and documents

CN-assisted oxidative cyclization of cyano cinnamates and styrene derivatives: A facile entry to 3-substituted chiral phthalides

The asymmetric dihydroxylation (AD) of o-cyano cinnamates and styrene derivatives leads to efficient construction of chiral phthalide frameworks in high optical purities. This unique reaction is characterized by unusual synergism between CN and osmate groups resulting in rate enhancement of the AD process. The method is amply demonstrated by the synthesis and the structural/stereochemical assignment of the natural products.