1374298-81-3

Basic information

• Product Name: methyl 2-[(2,6-dichlorophenyl)amino]-6-hydroxy-1H-benzimidazole-5-carboxylate
• Synonyms: methyl 2-[(2,6-dichlorophenyl)amino]-6-hydroxy-1H-benzimidazole-5-carboxylate
• CAS NO: 1374298-81-3
• Molecular Weight: 352.177
• Mol File: 1374298-81-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-[(2,6-dichlorophenyl)amino]-6-hydroxy-1H-benzimidazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-[(2,6-dichlorophenyl)amino]-6-hydroxy-1H-benzimidazole-5-carboxylate(1374298-81-3)
• EPA Substance Registry System: methyl 2-[(2,6-dichlorophenyl)amino]-6-hydroxy-1H-benzimidazole-5-carboxylate(1374298-81-3)

Safety Data

• Hazardous Substances Data: 1374298-81-3(Hazardous Substances Data)

Upstream product

• 153775-33-8 2,4-difluoro-5-nitro-benzoic acid 
• 179011-37-1 SRS₁₄-41 
• 1583-58-0 2,4-difluoro-benzoic acid 
• 89722-54-3 methyl 4-(benzylamino)-2-methoxy-5-nitrobenzoate 
• 1219013-92-9 ethyl 4-(benzylamino)-2-fluoro-5-nitrobenzoate 
• 106125-55-7 methyl 4-amino-2-hydroxy-5-nitrobenzoate 

Downstream Products

• 1374297-76-3 7-[(2,6-Dichlorophenyl)amino]-N-hexyl-2-methyl-8H-imidazo[4,5-e][1,3]benzoxazole-4-carboxamide 
• 1374297-72-9 7-[(2,6-Dichlorophenyl)amino]-N-(4-fluorophenyl)-2-methyl-8H-imidazo[4,5-e][1,3]benzoxazole-4-carboxamide 
• 1374298-88-0 methyl 7-amino-2-[(2,6-dichlorophenyl)amino]-6-hydroxy-1H-benzimidazole-5-carboxylate 
• 1374298-83-5 methyl 7-[(2,6-dichlorophenyl)amino]-2-methyl-8H-imidazo[4,5-e][1,3]benzoxazole-4-carboxylate 
• 1374298-82-4 methyl 2-[(2,6-dichlorophenyl)amino]-6-hydroxy-7-nitro-1H-benzimidazole-5-carboxylate 
• 1374298-79-9 7-[(2,6-dichlorophenyl)amino]-2-methyl-8H-imidazo[4,5-e][1,3]benzoxazole-4-carboxylic acid 

Relevant articles and documents

Tricyclic Compounds As mPGES-1 Inhibitors

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.