1374988-40-5

Basic information

• Product Name: 3-oxo-2-(2-phenylethyl)-2,3-dihydro-1,2-benzothiazole-6-sulfonamide 1,1-dioxide
• Synonyms: 3-oxo-2-(2-phenylethyl)-2,3-dihydro-1,2-benzothiazole-6-sulfonamide 1,1-dioxide
• CAS NO: 1374988-40-5
• Molecular Weight: 366.419
• Mol File: 1374988-40-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-oxo-2-(2-phenylethyl)-2,3-dihydro-1,2-benzothiazole-6-sulfonamide 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-oxo-2-(2-phenylethyl)-2,3-dihydro-1,2-benzothiazole-6-sulfonamide 1,1-dioxide(1374988-40-5)
• EPA Substance Registry System: 3-oxo-2-(2-phenylethyl)-2,3-dihydro-1,2-benzothiazole-6-sulfonamide 1,1-dioxide(1374988-40-5)

Safety Data

• Hazardous Substances Data: 1374988-40-5(Hazardous Substances Data)

Upstream product

• 717-44-2 4-methylbenzo-1,3-disulfonamide 
• 14121-27-8 3-oxo-2,3-dihydro-1,2-benzothiazole-6-sulfonamide 1,1-dioxide 
• 103-63-9 1-phenyl-2-bromoethane 
• 2767-77-3 toluene-2,4-disulfonyl dichloride 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

X-ray crystallography-promoted drug design of carbonic anhydrase inhibitors

1-N-Alkylated-6-sulfamoyl saccharin derivatives were prepared and assayed as carbonic anhydrase inhibitors (CAIs). During X-ray crystallographic experiments an unexpected hydrolysis of the isothiazole ring was evidenced which allowed us to prepare highly

Glyoxalase 1 and 2 enzyme inhibitory activity of 6-sulfamoylsaccharin and sulfocoumarin derivates

The glyoxalase enzymes represent a cellular defence system against the accumulation of cytotoxic α-oxoaldehydes leading to apoptosis. The potential of glyoxalase inhibitors to act as novel anti-cancer agents for drugresistant tumours that over-express gly