1375004-99-1

Basic information

• Product Name: (Z)-4-hydroxy-4'-methoxystilbene
• Synonyms: (Z)-4-hydroxy-4'-methoxystilbene
• CAS NO: 1375004-99-1
• Molecular Weight: 226.275
• Mol File: 1375004-99-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-4-hydroxy-4'-methoxystilbene(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-hydroxy-4'-methoxystilbene(1375004-99-1)
• EPA Substance Registry System: (Z)-4-hydroxy-4'-methoxystilbene(1375004-99-1)

Safety Data

• Hazardous Substances Data: 1375004-99-1(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 2746-25-0 p-Methoxybenzyl bromide 
• 1530-38-7 ((4-methoxyphenyl)methyl)triphenylphosphonium bromide 
• 1012-12-0 4-(trimethylsiloxy)benzaldehyde 
• 637-69-4 4-Methoxystyrene 
• 106-41-2 4-bromo-phenol 

Relevant articles and documents

Syntheses of polyfunctionalized resveratrol derivatives using Wittig and Heck protocols

Improved protocols for Wittig reaction and palladium-catalyzed Heck coupling give expedient access to a series of unprecedented polyfunctionalized artificial-resveratrol derivatives. In the modified Wittig protocol, trimethylsilyl was used as a highly valuable protective group of the phenolic functions of starting aromatic materials. A clean O-alkylation of hydroxylated stilbenes with ethylene carbonate was also conducted. Thus, Wittig reaction followed by hydroxyethylation take place one-pot with only carbon dioxide as waste. Additionally, a palladium-catalyzed Heck coupling strategy was developed by using ferrocenyl phosphane ligands, and multi-functionalized hydroxylated stilbenes were obtained without the need of any protection/deprotection sequence. Up to six functional groups are introduced by these procedures, which limit the number of reactions steps, the waste toxicity, and the use of costly reagents.