1375353-15-3Relevant articles and documents
New synthetic inhibitors of fatty acid synthase with anticancer activity
Turrado, Carlos,Puig, Teresa,García-Cárceles, Javier,Artola, Marta,Benhamú, Bellinda,Ortega-Gutiérrez, Silvia,Relat, Joana,Oliveras, Gloria,Blancafort, Adriana,Haro, Diego,Marrero, Pedro F.,Colomer, Ramón,López-Rodríguez, María L.
, p. 5013 - 5023 (2012/07/30)
Fatty acid synthase (FASN) is a lipogenic enzyme that is highly expressed in different human cancers. Here we report the development of a new series of polyphenolic compounds 5-30 that have been evaluated for their cytotoxic capacity in SK-Br3 cells, a hu