137571-38-1Relevant articles and documents
Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors
Dias, Marcio Vinícius Bertacine,Ferreira, Glaucio Monteiro,Kronenberger, Thales,Parise-Filho, Roberto,Pavan, Fernando Rogério,Poso, Antti,Ribeiro, Jo?o Augusto,Tavares, Maurício Temotheo,Trossini, Gustavo Henrique Goulart,da Silva Santos, Soraya,de Souza, Alfredo Danilo Ferreira
, (2020/07/03)
The enzyme dihydrofolate reductase from M. tuberculosis (MtDHFR) has a high unexploited potential to be a target for new drugs against tuberculosis (TB), due to its importance for pathogen survival. Preliminary studies have obtained fragment-like molecule
SYNTHESIS AND SPECTRAL STUDIES OF ALKYL-3- BENZOATES AND THEIR PHENYL SULFONYL DERIVATIVES
El-Bardan, Ali A.,Gohar, Gamal A.,El-Zahraa, Fatma,El-Hegazy, M.,Hamed, Ezzat A.
, p. 147 - 152 (2007/10/02)
New methyl and ethyl-3- benzoates and their corresponding phenyl sulfonyl derivatives have been synthesized and identified by UV, IR and 1H-NMR.Both phenylthio 1 and 2 as well as phenyl sulfonyl derivatives 3 and 4 showed a linear relationship between chemical shift δ ppm of the benzylic protons and ?-Hammett constants. Key words: Arylthio; aryl sulfonyl benzoates, 1H-NMR.