1376654-81-7Relevant articles and documents
Scalable, divergent synthesis of meroterpenoids via "borono- sclareolide"
Dixon, Darryl D.,Lockner, Jonathan W.,Zhou, Qianghui,Baran, Phil S.
, p. 8432 - 8435 (2012/07/14)
A scalable, divergent synthesis of bioactive meroterpenoids has been developed. A key component of this work is the invention of "borono- sclareolide", a terpenyl radical precursor that enables gram-scale preparation of (+)-chromazonarol. Subsequent synthetic operations on this key intermediate permit rapid access to a variety of related meroterpenoids, many of which possess important biological activity.