1376761-87-3

Basic information

• Product Name: 8-(benzyloxy)-6-chloroimidazo[1,2-b]pyridazine
• Synonyms: 8-(benzyloxy)-6-chloroimidazo[1,2-b]pyridazine
• CAS NO: 1376761-87-3
• Molecular Weight: 259.695
• Mol File: 1376761-87-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 8-(benzyloxy)-6-chloroimidazo[1,2-b]pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(benzyloxy)-6-chloroimidazo[1,2-b]pyridazine(1376761-87-3)
• EPA Substance Registry System: 8-(benzyloxy)-6-chloroimidazo[1,2-b]pyridazine(1376761-87-3)

Safety Data

• Hazardous Substances Data: 1376761-87-3(Hazardous Substances Data)

Upstream product

• 933190-51-3 8-bromo-6-chloro-imidazo[1,2-b]pyridazine 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1376761-86-2 imidazo[1,2-b]pyridazin-8-yl 4-methylbenzenesulfonate 

Relevant articles and documents

SUBSTITUTED FUSED AROMATIC RING DERIVATIVE, COMPOSITION AND USE THEREOF

Provided are a substituted fused aromatic ring derivative, a composition containing the compound, and a use thereof. The substituted fused aromatic ring derivative is a compound represented by formula (I) or a tautomer, stereoisomer, prodrug, crystal form, pharmaceutically acceptable salt, hydrate or solvate thereof. The compound and the composition can be used to treat various protein tyrosine kinase-mediated diseases or disorders.

Alkynyl (hetero) aromatic compounds for inhibiting activity of protein kinase

The invention relates to alkynyl (hetero) aromatic compounds for inhibiting activity of protein tyrosine kinase. The invention further relates to a pharmaceutical composition containing the alkynyl (hetero) aromatic compounds, and preparation and application of the alkynyl (hetero) aromatic compounds. Specifically, the invention discloses the alkynyl (hetero) aromatic compound shown in an equation (I) and pharmaceutically acceptable salts, stereoisomers, solvates, hydrates, crystal forms, prodrugs and isotopic variants of the alkynyl (hetero) aromatic compound shown in the equation (I). The alkynyl (hetero) aromatic compounds can be used for treating and/or preventing protein tyrosine kinase-related diseases, such as preventing tumors.

SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF

Provided herein are novel substituted urea derivatives, and pharmaceutical compositions thereof. Also provided herein are uses of the compounds or pharmaceutical compositions thereof for preventing, managing, treating or lessening a proliferative disease, andmodulating the activity of protein kinase.