137743-34-1Relevant articles and documents
Structure-Activity Relationships Associated with 3,4,5-Triphenyl-1H-pyrazole-1-nonanoic Acid, a Nonprostanoid Prostacyclin Mimetic
Meanwell, Nicholas A.,Rosenfeld, Michael J.,Wright, J. J. Kim,Brassard, Catherine L.,Buchanan, John O.,et al.
, p. 389 - 397 (2007/10/02)
A series of phenylated pyrazoloalkanoic acid derivatives were synthesized and evaluated as inhibitors of ADP-induced human platelet aggregation. 3,4,5-Triphenyl-1H-pyrazole-1-nonanoic acid (8d), with an IC50 of 0.4 μM, was the most potent inhibitor identi