137929-12-5

Basic information

• Product Name: Thiazole, 2-phenyl-4-(trifluoromethyl)-
• CAS NO: 137929-12-5
• Molecular Formula: C10H6F3NS
• Molecular Weight: 229.226
• Mol File: 137929-12-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Thiazole, 2-phenyl-4-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiazole, 2-phenyl-4-(trifluoromethyl)-(137929-12-5)
• EPA Substance Registry System: Thiazole, 2-phenyl-4-(trifluoromethyl)-(137929-12-5)

Safety Data

• Hazardous Substances Data: 137929-12-5(Hazardous Substances Data)

Upstream product

• 433-26-1 1,1,1-trifluoro-3-diazo-2-oxopropane 
• 2227-79-4 benzenecarbothioamide 
• 1895006-01-5 dimesityl(trifluoromethyl)sulfonium trifluoromethanesulfonate 
• 141305-40-0 4-bromo-2-phenylthiazole 
• 137929-10-3 4,5-dihydro-2-phenyl-4-(trifluoromethyl)-1,3-thiazol-4-ol 

Downstream Products

• 141062-95-5 1,2-bis(2-phenyl-4-(trifluoromethyl)thiazol-5-yl)hexafluoro-1-cyclopentene 

Relevant articles and documents

A novel access to 4-trifluoromethyl-1,3-thiazole derivatives via an intermediate thiocarbonyl ylide

A Lewis acid catalyzed reaction of trifluoroacetyldiazomethane (CF3COCHN2) with thiourea occurs in boiling THF solution in the presence of BF3·OEt2 yielding 2-amino-4-trifluoromethyl-1,3-thiazole in a fair yield

Synthesis of Trifluoromethylthiazoles and Their Application to Azo Dyes

3-Bromo-1,1,1-trifluoropropan-2-one (2) reacted with thiourea and N-monosubstituted thiourea to give the corresponding 4-trifluoromethylthiazoles, respectively.In the reactions with N,N'-diphenylthiourea and thioamides, the considerably stable intermediat