13795-37-4Relevant articles and documents
A novel kinetically-controlled peptide synthesis - Dramatic increase of chemical yield with retention of chiral integrity
Shieh, Wen-Chung,Carlson, John A.,Shore, Michael E.
, p. 7167 - 7170 (1999)
Peptide synthesis employing the highly selective reaction of isobutyl chloroformate at the carboxyl group of the N-protected amino acid, almost to the exclusion of the amino group of the C-protected amino acid, is described. This one-stage, kinetically-controlled strategy remarkably affords peptides with excellent optical purity in high chemical yields.
N,N'-Bis(2-oxo-3-oxazolidinyl)phosphorodiamidic Azide: A Useful Coupling Agent in Peptide Synthesis
Katti, S. B.,Misra, P. K.,Haq, W.,Mathur, K. B.
, p. 3 - 4 (2007/10/02)
N,N'-Bis(2-oxo-3-oxazolidinyl)phosphorodiamidic azide (BOPA), has been developed as an efficient coupling reagent in peptide synthesis.Coupling reaction proceeds smoothly with no detectable racemization.
N-TERMINAL SUBSTITUENT AND SIDE-CHAIN INFLUENCES ON THE CHEMICAL SHIFTS OF PROTONS IN MODEL DIPEPTIDE SYSTEMS
Davies, John S.,Hakeem, Essam
, p. 1387 - 1392 (2007/10/02)
(1)H Chemical shift values of ester methyls in model dipeptide esters have been shown to be sensitive to (a) the nature and configuration of the constituent amino acids and (b) the spatial distance between the N-terminal aryl group and the ester protons.C