1379513-70-8

Basic information

• Product Name: (R)-quinuclidin-3-yl 2-(tert-butoxycarbonylamino)-2-(3-fluorophenyl)acetate
• Synonyms: (R)-quinuclidin-3-yl 2-(tert-butoxycarbonylamino)-2-(3-fluorophenyl)acetate
• CAS NO: 1379513-70-8
• Molecular Weight: 378.444
• Mol File: 1379513-70-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (R)-quinuclidin-3-yl 2-(tert-butoxycarbonylamino)-2-(3-fluorophenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-quinuclidin-3-yl 2-(tert-butoxycarbonylamino)-2-(3-fluorophenyl)acetate(1379513-70-8)
• EPA Substance Registry System: (R)-quinuclidin-3-yl 2-(tert-butoxycarbonylamino)-2-(3-fluorophenyl)acetate(1379513-70-8)

Safety Data

• Hazardous Substances Data: 1379513-70-8(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 7292-74-2 DL-2-(3-fluorophenyl)glycine 
• 142121-94-6 2-(tert-butoxycarbonylamino)-2-(3-fluorophenyl)acetic acid 
• 25333-42-0 (R)-quinuclidin-3-ol 

Downstream Products

• 1379513-71-9 (3R)-3-(2-(tert-butoxycarbonylamino)-2-(3-fluorophenyl)acetoxy)-1-(2-oxo-2-phenylethyl)-1-azoniabicyclo[2.2.2]octane bromide 

Relevant articles and documents

HETEROARYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES

The invention relates to novel compounds of formula (I) which are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

NOVEL COMPOUNDS

Compounds of formula (I) defined herein are both inhibitors of the phosphodiesterase 4 (PDE4) enzyme and muscarinic M3 receptor antagonists and are useful for the prevention and/or treatment of a disease of the respiratory tract characterized by airway obstruction.

GLYCINE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF

Alkaloid aminoester derivatives according to formula (I) and (VI) act as muscarinic receptor antagonists.