137960-00-0

Basic information

• Product Name: 3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-(1-oxo-2-propynyl)-, phenylmethyl ester, (R)-
• CAS NO: 137960-00-0
• Molecular Formula: C16H17NO4
• Molecular Weight: 287.315
• Mol File: 137960-00-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-(1-oxo-2-propynyl)-, phenylmethyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-(1-oxo-2-propynyl)-, phenylmethyl ester, (R)-(137960-00-0)
• EPA Substance Registry System: 3-Oxazolidinecarboxylic acid, 2,2-dimethyl-4-(1-oxo-2-propynyl)-, phenylmethyl ester, (R)-(137960-00-0)

Safety Data

• Hazardous Substances Data: 137960-00-0(Hazardous Substances Data)

Upstream product

• 133464-37-6 (4R)-4-formyl-2,2-dimethyloxazolidine-3-carboxylic acid benzyl ester 

Downstream Products

• 137960-05-5 N-(Benzyloxycarbonyl)-N,O-isopropylidene-β-oxo-3-phenoxy-(S)-tyrosinol 
• 143817-62-3 C₃₈H₄₈N₂O₉ 
• 143817-61-2 C₃₈H₄₈N₂O₉ 
• 137960-04-4 (R)-4-(5-Methoxy-4-phenoxy-cyclohexa-1,4-dienecarbonyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 137960-03-3 (R)-4-(4-Methoxy-5-phenoxy-cyclohexa-1,4-dienecarbonyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 137960-11-3 (R)-4-(3-Methoxy-4-phenoxy-benzoyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 137960-10-2 (R)-4-(4-Methoxy-3-phenoxy-benzoyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 137960-06-6 (R)-4-(4-Hydroxy-benzoyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 

Relevant articles and documents

Synthesis of Functionalized Aryloxy 1,3-Butadienes and Their Transformation to Diaryl Ethers via Diels-Alder Cycloaddition Reactions

The Diels-Alder reaction involving cycloaddition of aryloxy-substituted 1,3-butadienes with appropriate acetylenic electrophiles, followed by aromatization of the newly formed cyclohexadiene ring, has been used for the synthesis of diaryl ethers.The functionalized aryloxy 1,3-butadienes employed in this study were prepared by either of two methods: (1) methylenation of aryl esters via the Tebbe or related reagents, and (2) from 1-(aryloxy)-2-propanone by a sequence of formylation or alkylthio methylenation, and subsequent enolsilylation.A tetrasubstituted butadiene containing two phenoxy groups at the 1 and 3 positions also was prepared by the latter method.The cycloaddition reactions of 2,3-dioxy-substituted dienes occurred in high yield, but, as expected, with no regioselectivity to furnish nearly equal mixtures of regioisomeric cycloadducts.In contrast, application of 1,2,3-trihetero-substituted dienes resulted in regiospecific cycloaddition reactions.Transformation of the cyclohexadiene cycloadducts to an aromatic ring was accomplished by dehydrogenation with DDQ or by elimination during the cycloaddition process of a molecule of an alkyl mercaptan.A chiral acetylenic ketone derived from D- or L-serine underwent condensation, without racemization, with aryloxy dienes to provide diaryl ethers related to the isodityrosine antibiotics.