1379614-89-7

Basic information

• Product Name: methyl (1R,2S,3S,10bR)-1-[(1E)-3-ethoxy-3-oxoprop-1-en-1-yl]-8,9-dimethoxy-3-methyl-2-[4-(trifluoromethyl)phenyl]-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline-3-carboxylate
• CAS NO: 1379614-89-7
• Molecular Weight: 547.571
• Mol File: 1379614-89-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (1R,2S,3S,10bR)-1-[(1E)-3-ethoxy-3-oxoprop-1-en-1-yl]-8,9-dimethoxy-3-methyl-2-[4-(trifluoromethyl)phenyl]-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (1R,2S,3S,10bR)-1-[(1E)-3-ethoxy-3-oxoprop-1-en-1-yl]-8,9-dimethoxy-3-methyl-2-[4-(trifluoromethyl)phenyl]-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline-3-carboxylate(1379614-89-7)
• EPA Substance Registry System: methyl (1R,2S,3S,10bR)-1-[(1E)-3-ethoxy-3-oxoprop-1-en-1-yl]-8,9-dimethoxy-3-methyl-2-[4-(trifluoromethyl)phenyl]-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline-3-carboxylate(1379614-89-7)

Safety Data

• Hazardous Substances Data: 1379614-89-7(Hazardous Substances Data)

Upstream product

• 5445-17-0 Methyl 2-bromopropionate 
• 20232-39-7 3,4-dihydro-6,7-dimethoxyisoquinoline hydrochloride 
• 95123-61-8 4-(trifluoromethyl)cinnamaldehyde 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Relevant articles and documents

Asymmetric synthesis of hexahydropyrrolo-isoquinolines by an organocatalytic three-component reaction

Merging three in one by a three-component organocatalytic asymmetric reaction of imines and α-bromoesters or ketones with α,β- unsaturated aldehydes provides optically active pyrrolo-isoquinolines-an important class of molecules in life science. The reaction proceeds with excellent enantioselectivity and a number of transformations of the products obtained demonstrated the potential of the new reaction. Copyright