1379689-46-9

Basic information

• Product Name: (1R,2R)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,2-bis(4-fluorophenyl)ethanol
• Synonyms: (1R,2R)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,2-bis(4-fluorophenyl)ethanol
• CAS NO: 1379689-46-9
• Molecular Weight: 328.362
• Mol File: 1379689-46-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,2-bis(4-fluorophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,2-bis(4-fluorophenyl)ethanol(1379689-46-9)
• EPA Substance Registry System: (1R,2R)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,2-bis(4-fluorophenyl)ethanol(1379689-46-9)

Safety Data

• Hazardous Substances Data: 1379689-46-9(Hazardous Substances Data)

Upstream product

• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 327628-46-6 (2R,3S)-2,3-bis(4-fluorophenyl)oxirane 

Relevant articles and documents

Enantioselective synthesis of β-pyrazole-substituted alcohols through an asymmetric ring-opening reaction of meso-epoxides

An efficient and practical synthesis of optically pure β-pyrazole- substituted alcohols was achieved by an asymmetric ring-opening reaction of meso-epoxides with pyrazole derivatives as the nucleophile. In the presence of 1 mol % of an N,N′-dioxide-Sc(OTf)3 complex, excellent enantioselectivity and yields were obtained from meso-epoxides. The process could also be used for a mixture of cis- and trans-stilbene oxides. A proposed transition-state model is provided. Copyright