1379800-25-5

Basic information

• Product Name: C₄₇H₅₄N₄O₁₈
• Synonyms: C₄₇H₅₄N₄O₁₈
• CAS NO: 1379800-25-5
• Molecular Weight: 962.962
• Mol File: 1379800-25-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₄₇H₅₄N₄O₁₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₇H₅₄N₄O₁₈(1379800-25-5)
• EPA Substance Registry System: C₄₇H₅₄N₄O₁₈(1379800-25-5)

Safety Data

• Hazardous Substances Data: 1379800-25-5(Hazardous Substances Data)

Upstream product

• 65055-19-8 2,3-bis(acetyloxy)benzoyl chloride 
• 486-79-3 2,3-diacetoxybenzoic acid 

Relevant articles and documents

Iron transport-mediated drug delivery: Practical syntheses and in vitro antibacterial studies of tris-catecholate siderophore-aminopenicillin conjugates reveals selectively potent antipseudomonal activity

An artificial tris-catecolate siderophore with a tripodal backbone and its conjugates with ampicillin and amoxicillin were synthesized. Both conjugates exhibited significantly enhanced in vitro antibacterial activities against Gram-negative species compared to the parent drugs, especially against Pseudomonas aeruginosa. The conjugates appeared to be assimilated by an induced bacterial iron transport process as their activities were inversely related to iron concentration. The easily synthesized tris-catecolate siderophore has great potential for future development of various drug conjugates to target antibiotic-resistant Gram-negative bacteria.